High Frequency and Poor Outcome of Philadelphia Chromosome–Like Acute Lymphoblastic Leukemia in Adults

PURPOSE: Philadelphia chromosome (Ph) –like acute lymphoblastic leukemia (ALL) is a high-risk subtype of childhood ALL characterized by kinase-activating alterations that are amenable to treatment with tyrosine kinase inhibitors. We sought to define the prevalence and genomic landscape of Ph-like AL...

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Publicado en:J Clin Oncol
Main Authors: Roberts, Kathryn G., Gu, Zhaohui, Payne-Turner, Debbie, McCastlain, Kelly, Harvey, Richard C., Chen, I-Ming, Pei, Deqing, Iacobucci, Ilaria, Valentine, Marcus, Pounds, Stanley B., Shi, Lei, Li, Yongjin, Zhang, Jinghui, Cheng, Cheng, Rambaldi, Alessandro, Tosi, Manuela, Spinelli, Orietta, Radich, Jerald P., Minden, Mark D., Rowe, Jacob M., Luger, Selina, Litzow, Mark R., Tallman, Martin S., Wiernik, Peter H., Bhatia, Ravi, Aldoss, Ibrahim, Kohlschmidt, Jessica, Mrózek, Krzysztof, Marcucci, Guido, Bloomfield, Clara D., Stock, Wendy, Kornblau, Stephen, Kantarjian, Hagop M., Konopleva, Marina, Paietta, Elisabeth, Willman, Cheryl L., Mullighan, Charles G.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Clinical Oncology 2017
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ORIGINAL REPORTS
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5455698/
https://ncbi.nlm.nih.gov/pubmed/27870571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2016.69.0073
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