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Active site restructuring regulates ligand recognition in class A penicillin-binding proteins
Bacterial cell division is a complex, multimolecular process that requires biosynthesis of new peptidoglycan by penicillin-binding proteins (PBPs) during cell wall elongation and septum formation steps. Streptococcus pneumoniae has three bifunctional (class A) PBPs that catalyze both polymerization...
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Main Authors: | , , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
National Academy of Sciences
2005
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC545533/ https://ncbi.nlm.nih.gov/pubmed/15637155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407186102 |
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