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Different GABA(A) receptor subtypes mediate the anxiolytic, abuse-related, and motor effects of benzodiazepine-like drugs in primates

Benzodiazepines exert their effects by binding to multiple subtypes of the GABA(A) receptor, the predominant subtypes in the brain being those that contain α(1)-, α(2)-, α(3)-, and α(5)-subunits. To understand the potentially different roles of these subtypes in the therapeutic and side effects of b...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Rowlett, James K., Platt, Donna M., Lelas, Snjezana, Atack, John R., Dawson, Gerard R.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2005
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC545524/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15644443/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0405621102
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