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Benzodiazepine + neuroactive steroid combinations in rats: Anxiolytic-like and discriminative stimulus effects

RATIONALE: Benzodiazepines are effective anxiolytics, hypnotics, and anticonvulsants but unwanted side effects, including abuse potential, limit their use. A possible strategy to increase the therapeutic index of this drug class is to combine benzodiazepines with neuroactive steroids. OBJECTIVES: Th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Psychopharmacology (Berl)
Hauptverfasser: Gunter, Barak W., Jones, Sherman A., Paul, Ian A., Platt, Donna M., Rowlett, James K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6334648/
https://ncbi.nlm.nih.gov/pubmed/27356519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-016-4369-8
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