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Neuroactive steroid stereospecificity of ethanol-like discriminative stimulus effects in monkeys
Positive modulation of GABA(A) and antagonism of NMDA receptors mediate the discriminative stimulus effects of ethanol. Endogenous neuroactive steroids produce effects similar to ethanol suggesting that these steroids may modulate ethanol addiction. The 4 isomers of the functional esters at C-3 of t...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2562878/ https://ncbi.nlm.nih.gov/pubmed/18436788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.137315 |
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