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Different GABA(A) receptor subtypes mediate the anxiolytic, abuse-related, and motor effects of benzodiazepine-like drugs in primates

Benzodiazepines exert their effects by binding to multiple subtypes of the GABA(A) receptor, the predominant subtypes in the brain being those that contain α(1)-, α(2)-, α(3)-, and α(5)-subunits. To understand the potentially different roles of these subtypes in the therapeutic and side effects of b...

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Hlavní autoři: Rowlett, James K., Platt, Donna M., Lelas, Snjezana, Atack, John R., Dawson, Gerard R.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC545524/
https://ncbi.nlm.nih.gov/pubmed/15644443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405621102
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