High-Mobility Group Box 1 Disrupts Metabolic Function with Cigarette Smoke Exposure in a Ceramide-Dependent Manner

We have previously found that cigarette smoke disrupts metabolic function, in part, by increasing muscle ceramide accrual. To further our understanding of this, we sought to determine the role of the cytokine high-mobility group box 1 (HMGB1), which is increased with smoke exposure, in smoke-induced...

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Taylor, Oliver J., Thatcher, Mikayla O., Carr, Sheryl T., Gibbs, Jonathan L., Trumbull, Annie M., Harrison, Mitchell E., Winden, Duane R., Pearson, Mackenzie J., Tippetts, Trevor S., Holland, William L., Reynolds, Paul R., Bikman, Benjamin T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5455007/
https://ncbi.nlm.nih.gov/pubmed/28531105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18051099
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