High-Mobility Group Box 1 Disrupts Metabolic Function with Cigarette Smoke Exposure in a Ceramide-Dependent Manner

We have previously found that cigarette smoke disrupts metabolic function, in part, by increasing muscle ceramide accrual. To further our understanding of this, we sought to determine the role of the cytokine high-mobility group box 1 (HMGB1), which is increased with smoke exposure, in smoke-induced...

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Publié dans:Int J Mol Sci
Auteurs principaux: Taylor, Oliver J., Thatcher, Mikayla O., Carr, Sheryl T., Gibbs, Jonathan L., Trumbull, Annie M., Harrison, Mitchell E., Winden, Duane R., Pearson, Mackenzie J., Tippetts, Trevor S., Holland, William L., Reynolds, Paul R., Bikman, Benjamin T.
Format: Artigo
Langue:Inglês
Publié: MDPI 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5455007/
https://ncbi.nlm.nih.gov/pubmed/28531105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18051099
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