Cigarette smoke increases cardiomyocyte ceramide accumulation and inhibits mitochondrial respiration

BACKGROUND: Cigarette smoking is a common and lethal worldwide habit, with considerable mortality stemming from its deleterious effects on heart function. While current theories posit altered blood lipids and fibrinogen metabolism as likely mediators, none have explored the role of the sphingolipid...

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Detalhes bibliográficos
Publicado no:BMC Cardiovasc Disord
Main Authors: Tippetts, Trevor S, Winden, Duane R, Swensen, Adam C, Nelson, Michael B, Thatcher, Mikayla O, Saito, Rex R, Condie, Tyler B, Simmons, Kurtis J, Judd, Allan M, Reynolds, Paul R, Bikman, Benjamin T
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4247675/
https://ncbi.nlm.nih.gov/pubmed/25416336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2261-14-165
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