Cigarette smoke increases cardiomyocyte ceramide accumulation and inhibits mitochondrial respiration

BACKGROUND: Cigarette smoking is a common and lethal worldwide habit, with considerable mortality stemming from its deleterious effects on heart function. While current theories posit altered blood lipids and fibrinogen metabolism as likely mediators, none have explored the role of the sphingolipid...

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Udgivet i:BMC Cardiovasc Disord
Main Authors: Tippetts, Trevor S, Winden, Duane R, Swensen, Adam C, Nelson, Michael B, Thatcher, Mikayla O, Saito, Rex R, Condie, Tyler B, Simmons, Kurtis J, Judd, Allan M, Reynolds, Paul R, Bikman, Benjamin T
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4247675/
https://ncbi.nlm.nih.gov/pubmed/25416336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2261-14-165
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