Lipopolysaccharide Disrupts Mitochondrial Physiology in Skeletal Muscle via Disparate Effects on Sphingolipid Metabolism

Lipopolysaccharides (LPS) are prevalent pathogenic molecules that are found within tissues and blood. Elevated circulating LPS is a feature of obesity and sepsis, both of which are associated with mitochondrial abnormalities that are key pathological features of LPS excess. However, the mechanism of...

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Detalhes bibliográficos
Publicado no:Shock
Main Authors: Hansen, Melissa E., Simmons, Kurtis J., Tippetts, Trevor S., Thatcher, Mikayla O., Saito, Rex R., Hubbard, Sheryl T., Trumbull, Annie M., Parker, Brian A., Taylor, Oliver J., Bikman, Benjamin T.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2015
Assuntos:
Basic Science Aspects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851226/
https://ncbi.nlm.nih.gov/pubmed/26529656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000000468
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