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Inhibition of Autophagy Promotes Salinomycin-Induced Apoptosis via Reactive Oxygen Species-Mediated PI3K/AKT/mTOR and ERK/p38 MAPK-Dependent Signaling in Human Prostate Cancer Cells

Recently, the interplay between autophagy and apoptosis has become an important factor in chemotherapy for cancer treatment. Inhibition of autophagy may be an effective strategy to improve the treatment of chemo-resistant cancer by consistent exposure to chemotherapeutic drugs. However, no reports h...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Kim, Kwang-Youn, Park, Kwang-Il, Kim, Sang-Hun, Yu, Sun-Nyoung, Park, Sul-Gi, Kim, Young Woo, Seo, Young-Kyo, Ma, Jin-Yeul, Ahn, Soon-Cheol
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454997/
https://ncbi.nlm.nih.gov/pubmed/28524116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18051088
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