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Kaempferol Inhibits Angiogenesis by Suppressing HIF-1α and VEGFR2 Activation via ERK/p38 MAPK and PI3K/Akt/mTOR Signaling Pathways in Endothelial Cells

Kaempferol has been shown to inhibit vascular formation in endothelial cells. However, the underlying mechanisms are not fully understood. In the present study, we evaluated whether kaempferol exerts antiangiogenic effects by targeting extracellular signal-regulated kinase (ERK)/p38 mitogen-activate...

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Detalhes bibliográficos
Publicado no:Prev Nutr Food Sci
Autor principal: Kim, Gi Dae
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Society of Food Science and Nutrition 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5758096/
https://ncbi.nlm.nih.gov/pubmed/29333385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3746/pnf.2017.22.4.320
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