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Brain RNA-Seq Profiling of the Mucopolysaccharidosis Type II Mouse Model

Lysosomal storage disorders (LSDs) are a group of about 50 genetic metabolic disorders, mainly affecting children, sharing the inability to degrade specific endolysosomal substrates. This results in failure of cellular functions in many organs, including brain that in most patients may go through pr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Salvalaio, Marika, D’Avanzo, Francesca, Rigon, Laura, Zanetti, Alessandra, D’Angelo, Michela, Valle, Giorgio, Scarpa, Maurizio, Tomanin, Rosella
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454982/
https://ncbi.nlm.nih.gov/pubmed/28513549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18051072
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