Sensitive and specific detection of microRNAs by northern blot analysis using LNA-modified oligonucleotide probes

We describe here a new method for highly efficient detection of microRNAs by northern blot analysis using LNA (locked nucleic acid)-modified oligonucleotides. In order to exploit the improved hybridization properties of LNA with their target RNA molecules, we designed several LNA-modified oligonucle...

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Bibliographic Details
Main Authors: Válóczi, Anna, Hornyik, Csaba, Varga, Nóra, Burgyán, József, Kauppinen, Sakari, Havelda, Zoltán
Format: Artigo
Language:Inglês
Published: Oxford University Press 2004
Subjects:
NAR Methods Online
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC545470/
https://ncbi.nlm.nih.gov/pubmed/15598818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gnh171
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