LNA-enhanced detection of single nucleotide polymorphisms in the apolipoprotein E

Genotyping of single nucleotide polymorphisms (SNPs) in large populations presents a great challenge, especially if the SNPs are embedded in GC-rich regions, such as the codon 112 SNP in the human apolipoprotein E (apoE). In the present study, we have used immobilized locked nucleic acid (LNA) captu...

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Bibliographische Detailangaben
Hauptverfasser: Jacobsen, Nana, Bentzen, Joan, Meldgaard, Michael, Jakobsen, Mogens Havsteen, Fenger, Mogens, Kauppinen, Sakari, Skouv, Jan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2002
Schlagworte:
NAR Methods Online
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC140560/
https://ncbi.nlm.nih.gov/pubmed/12364617
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