OligoDesign: optimal design of LNA (locked nucleic acid) oligonucleotide capture probes for gene expression profiling

We report the development of new software, OligoDesign, which provides optimal design of LNA (locked nucleic acid) substituted oligonucleotides for functional genomics applications. LNAs constitute a novel class of bicyclic RNA analogs having an exceptionally high affinity and specificity toward the...

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Hlavní autoři: Tolstrup, Niels, Nielsen, Peter S., Kolberg, Jens G., Frankel, Annett M., Vissing, Henrik, Kauppinen, Sakari
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2003
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC168986/
https://ncbi.nlm.nih.gov/pubmed/12824412
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