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Sensitive and specific detection of microRNAs by northern blot analysis using LNA-modified oligonucleotide probes
We describe here a new method for highly efficient detection of microRNAs by northern blot analysis using LNA (locked nucleic acid)-modified oligonucleotides. In order to exploit the improved hybridization properties of LNA with their target RNA molecules, we designed several LNA-modified oligonucle...
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| Publicat a: | Nucleic Acids Res |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC545470/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15598818/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gnh171 |
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