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Discrimination of cytosolic self and non-self RNA by RIG-I-like receptors

RIG-I-like receptors (RLRs) are cytosolic innate immune sensors that detect pathogenic RNA and induce a systemic antiviral response. During the last decade, many studies focused on their molecular characterization and the identification of RNA agonists. Therefore, it became more and more clear that...

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Pubblicato in:J Biol Chem
Autori principali: Lässig, Charlotte, Hopfner, Karl-Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454087/
https://ncbi.nlm.nih.gov/pubmed/28411239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R117.788398
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