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RIG-I ATPase Activity and Discrimination of Self-RNA versus Non-Self-RNA
Many RNA viruses are detected by retinoic acid-inducible gene i (RIG-I), a cytoplasmic sensor that triggers an antiviral response upon binding non-self-RNA that contains a stretch of double-stranded RNA (dsRNA) bearing a base-paired 5′ ppp nucleotide. To gain insight into how RIG-I discriminates bet...
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| Publié dans: | mBio |
|---|---|
| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society of Microbiology
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4358010/ https://ncbi.nlm.nih.gov/pubmed/25736886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02349-14 |
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