Integrin-Kindlin3 requirements for microglial motility in vivo are distinct from those for macrophages

Microglia play a critical role in the development and homeostasis of the CNS. While mobilization of microglia is critical for a number of pathologies, understanding of the mechanisms of their migration in vivo is limited and often based on similarities to macrophages. Kindlin3 deficiency as well as...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Meller, Julia, Chen, Zhihong, Dudiki, Tejasvi, Cull, Rebecca M., Murtazina, Rakhilya, Bal, Saswat K., Pluskota, Elzbieta, Stefl, Samantha, Plow, Edward F., Trapp, Bruce D., Byzova, Tatiana V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5453700/
https://ncbi.nlm.nih.gov/pubmed/28570266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.93002
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