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The integrin coactivator Kindlin-2 plays a critical role in angiogenesis in mice and zebrafish
Kindlin-2, a widely distributed cytoskeletal protein, has been implicated in integrin activation, and its absence is embryonically lethal in mice and causes severe developmental defects in zebrafish. Knockdown of kindlin-2 levels in endothelial cells resulted in defective adhesive and migratory resp...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3100704/ https://ncbi.nlm.nih.gov/pubmed/21378273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-11-321182 |
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