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The Kindlin2-p53-SerpinB2 signaling axis is required for cellular senescence in breast cancer

In cancer, cellular senescence is a complex process that leads to inhibition of proliferation of cells that may develop a neoplastic phenotype. A plethora of signaling pathways, when dysregulated, have been shown to elicit a senescence response. Two well-known tumor suppressor pathways, controlled b...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Sossey-Alaoui, Khalid, Pluskota, Elzbieta, Szpak, Dorota, Plow, Edward F.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629707/
https://ncbi.nlm.nih.gov/pubmed/31308359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1774-z
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