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Tyrosine Phosphorylation of Integrin β(3) Regulates Kindlin-2 Binding and Integrin Activation
Kindlins are essential for integrin activation in cell systems and do so by working in a cooperative fashion with talin via their direct interaction with integrin β cytoplasmic tails (CTs). Kindlins interact with the membrane-distal NxxY motif, which is distinct from the talin-binding site within th...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2945529/ https://ncbi.nlm.nih.gov/pubmed/20702409 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C110.134247 |
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