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Site-specific Phosphorylation of Kindlin-3 Protein Regulates Its Capacity to Control Cellular Responses Mediated by Integrin α(IIb)β(3)

The contributions of integrins to cellular responses depend upon their activation, which is regulated by binding of proteins to their cytoplasmic tails. Kindlins are integrin cytoplasmic tail binding partners and are essential for optimal integrin activation, and kindlin-3 fulfills this role in hema...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Bialkowska, Katarzyna, Byzova, Tatiana V., Plow, Edward F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358261/
https://ncbi.nlm.nih.gov/pubmed/25609252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.634436
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