qPCR-High resolution melt analysis for drug susceptibility testing of Mycobacterium leprae directly from clinical specimens of leprosy patients

BACKGROUND: Real-Time PCR-High Resolution Melting (qPCR-HRM) analysis has been recently described for rapid drug susceptibility testing (DST) of Mycobacterium leprae. The purpose of the current study was to further evaluate the validity, reliability, and accuracy of this assay for M. leprae DST in c...

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Dades bibliogràfiques
Publicat a:PLoS Negl Trop Dis
Autors principals: Araujo, Sergio, Goulart, Luiz Ricardo, Truman, Richard W., Goulart, Isabela Maria B., Vissa, Varalakshmi, Li, Wei, Matsuoka, Masanori, Suffys, Philip, Fontes, Amanda B., Rosa, Patricia S., Scollard, David M., Williams, Diana L.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5453413/
https://ncbi.nlm.nih.gov/pubmed/28570560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005506
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