Real-Time PCR and High-Resolution Melt Analysis for Rapid Detection of Mycobacterium leprae Drug Resistance Mutations and Strain Types

Drug resistance surveillance and strain typing of Mycobacterium leprae are necessary to investigate ongoing transmission of leprosy in regions of endemicity. To enable wider implementation of these molecular analyses, novel real-time PCR–high-resolution melt (RT-PCR-HRM) assays without allele-specif...

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Hlavní autoři: Li, Wei, Matsuoka, Masanori, Kai, Masanori, Thapa, Pratibha, Khadge, Saraswoti, Hagge, Deanna A., Brennan, Patrick J., Vissa, Varalakshmi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2012
Témata:
Mycobacteriology and Aerobic Actinomycetes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295127/
https://ncbi.nlm.nih.gov/pubmed/22170923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.05183-11
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