Real-Time PCR and High-Resolution Melt Analysis for Rapid Detection of Mycobacterium leprae Drug Resistance Mutations and Strain Types

Drug resistance surveillance and strain typing of Mycobacterium leprae are necessary to investigate ongoing transmission of leprosy in regions of endemicity. To enable wider implementation of these molecular analyses, novel real-time PCR–high-resolution melt (RT-PCR-HRM) assays without allele-specif...

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Autores principales: Li, Wei, Matsuoka, Masanori, Kai, Masanori, Thapa, Pratibha, Khadge, Saraswoti, Hagge, Deanna A., Brennan, Patrick J., Vissa, Varalakshmi
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2012
Materias:
Mycobacteriology and Aerobic Actinomycetes
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295127/
https://ncbi.nlm.nih.gov/pubmed/22170923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.05183-11
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