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Rapid Detection of Multidrug-Resistant Mycobacterium tuberculosis by Use of Real-Time PCR and High-Resolution Melt Analysis

The current study describes the development of a unique real-time PCR assay for the detection of mutations conferring drug resistance in Mycobacterium tuberculosis. The rifampicin resistance determinant region (RRDR) of rpoB and specific regions of katG and the inhA promoter were targeted for the de...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ramirez, Melissa V., Cowart, Kelley C., Campbell, Patricia J., Morlock, Glenn P., Sikes, David, Winchell, Jonas M., Posey, James E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020863/
https://ncbi.nlm.nih.gov/pubmed/20810777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00812-10
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