Rapid Detection of Multidrug-Resistant Mycobacterium tuberculosis by Use of Real-Time PCR and High-Resolution Melt Analysis

The current study describes the development of a unique real-time PCR assay for the detection of mutations conferring drug resistance in Mycobacterium tuberculosis. The rifampicin resistance determinant region (RRDR) of rpoB and specific regions of katG and the inhA promoter were targeted for the de...

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Detalhes bibliográficos
Main Authors: Ramirez, Melissa V., Cowart, Kelley C., Campbell, Patricia J., Morlock, Glenn P., Sikes, David, Winchell, Jonas M., Posey, James E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Mycobacteriology and Aerobic Actinomycetes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020863/
https://ncbi.nlm.nih.gov/pubmed/20810777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00812-10
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