qPCR-High resolution melt analysis for drug susceptibility testing of Mycobacterium leprae directly from clinical specimens of leprosy patients

BACKGROUND: Real-Time PCR-High Resolution Melting (qPCR-HRM) analysis has been recently described for rapid drug susceptibility testing (DST) of Mycobacterium leprae. The purpose of the current study was to further evaluate the validity, reliability, and accuracy of this assay for M. leprae DST in c...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Araujo, Sergio, Goulart, Luiz Ricardo, Truman, Richard W., Goulart, Isabela Maria B., Vissa, Varalakshmi, Li, Wei, Matsuoka, Masanori, Suffys, Philip, Fontes, Amanda B., Rosa, Patricia S., Scollard, David M., Williams, Diana L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5453413/
https://ncbi.nlm.nih.gov/pubmed/28570560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005506
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