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Structural Biology of PrP Prions
Prion diseases are characterized by the deposition of amyloids, misfolded conformers of the prion protein. The misfolded conformation is self-replicating, by a mechanism solely enciphered in the conformation of the protein. Because of low solubility and heterogeneous aggregate sizes, the detailed at...
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| Veröffentlicht in: | Cold Spring Harb Perspect Med |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5453385/ https://ncbi.nlm.nih.gov/pubmed/28003279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a024455 |
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