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Structural Biology of PrP Prions

Prion diseases are characterized by the deposition of amyloids, misfolded conformers of the prion protein. The misfolded conformation is self-replicating, by a mechanism solely enciphered in the conformation of the protein. Because of low solubility and heterogeneous aggregate sizes, the detailed at...

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Bibliografski detalji
Izdano u:Cold Spring Harb Perspect Med
Glavni autori: Stubbs, Gerald, Stöhr, Jan
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5453385/
https://ncbi.nlm.nih.gov/pubmed/28003279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a024455
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