Shikonin-induced necroptosis is enhanced by the inhibition of autophagy in non-small cell lung cancer cells

BACKGROUND: Shikonin, a natural naphthoquinone pigment purified from Lithospermum erythrorhizon, induces necroptosis in various cancer types, but the mechanisms underlying the anticancer activity of shikonin in lung cancer are not fully understood. This study was designed to clarify whether shikonin...

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Dettagli Bibliografici
Pubblicato in:J Transl Med
Autori principali: Kim, Hyo-Jin, Hwang, Ki-Eun, Park, Do-Sim, Oh, Seon-Hee, Jun, Hong Young, Yoon, Kwon-Ha, Jeong, Eun-Taik, Kim, Hak-Ryul, Kim, Young-Suk
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5452303/
https://ncbi.nlm.nih.gov/pubmed/28569199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-017-1223-7
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