Shikonin-induced necroptosis is enhanced by the inhibition of autophagy in non-small cell lung cancer cells

BACKGROUND: Shikonin, a natural naphthoquinone pigment purified from Lithospermum erythrorhizon, induces necroptosis in various cancer types, but the mechanisms underlying the anticancer activity of shikonin in lung cancer are not fully understood. This study was designed to clarify whether shikonin...

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Bibliografski detalji
Izdano u:J Transl Med
Glavni autori: Kim, Hyo-Jin, Hwang, Ki-Eun, Park, Do-Sim, Oh, Seon-Hee, Jun, Hong Young, Yoon, Kwon-Ha, Jeong, Eun-Taik, Kim, Hak-Ryul, Kim, Young-Suk
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5452303/
https://ncbi.nlm.nih.gov/pubmed/28569199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-017-1223-7
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