Shikonin-induced necroptosis is enhanced by the inhibition of autophagy in non-small cell lung cancer cells

BACKGROUND: Shikonin, a natural naphthoquinone pigment purified from Lithospermum erythrorhizon, induces necroptosis in various cancer types, but the mechanisms underlying the anticancer activity of shikonin in lung cancer are not fully understood. This study was designed to clarify whether shikonin...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Kim, Hyo-Jin, Hwang, Ki-Eun, Park, Do-Sim, Oh, Seon-Hee, Jun, Hong Young, Yoon, Kwon-Ha, Jeong, Eun-Taik, Kim, Hak-Ryul, Kim, Young-Suk
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5452303/
https://ncbi.nlm.nih.gov/pubmed/28569199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-017-1223-7
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