Shikonin-induced necroptosis is enhanced by the inhibition of autophagy in non-small cell lung cancer cells

BACKGROUND: Shikonin, a natural naphthoquinone pigment purified from Lithospermum erythrorhizon, induces necroptosis in various cancer types, but the mechanisms underlying the anticancer activity of shikonin in lung cancer are not fully understood. This study was designed to clarify whether shikonin...

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Vydáno v:J Transl Med
Hlavní autoři: Kim, Hyo-Jin, Hwang, Ki-Eun, Park, Do-Sim, Oh, Seon-Hee, Jun, Hong Young, Yoon, Kwon-Ha, Jeong, Eun-Taik, Kim, Hak-Ryul, Kim, Young-Suk
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5452303/
https://ncbi.nlm.nih.gov/pubmed/28569199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-017-1223-7
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