Celecoxib and sulindac inhibit TGF-β1-induced epithelial-mesenchymal transition and suppress lung cancer migration and invasion via downregulation of sirtuin 1

The non-steroidal anti-inflammatory drugs (NSAIDs) celecoxib and sulindac have been reported to suppress lung cancer migration and invasion. The class III deacetylase sirtuin 1 (SIRT1) possesses both pro- and anticarcinogenic properties. However, its role in inhibition of lung cancer cell epithelial...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Cha, Byong-Ki, Kim, Young-Suk, Hwang, Ki-Eun, Cho, Kyung-Hwa, Oh, Seon-Hee, Kim, Byoung-Ryun, Jun, Hong-Young, Yoon, Kwon-Ha, Jeong, Eun-Taik, Kim, Hak-Ryul
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5302984/
https://ncbi.nlm.nih.gov/pubmed/27528025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11127
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