Tiul1 and TGIF are Involved in Downregulation of TGFβ1-induced IgA Isotype Expression

TGF-β1 is well known to induce Ig germ-line α (GLα) transcription and subsequent IgA isotype class switching recombination (CSR). Homeodomain protein TG-interacting factor (TGIF) and E3-ubiquitin ligases TGIF interacting ubiquitin ligase 1 (Tiul1) are implicated in the negative regulation of TGF-β s...

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Main Authors: Park, Kyoung-Hoon, Nam, Eun-Hee, Seo, Goo-Young, Seo, Su Ryeon, Kim, Pyeung-Hyeun
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Association of Immunologists 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816958/
https://ncbi.nlm.nih.gov/pubmed/20157612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4110/in.2009.9.6.248
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https://ncbi.nlm.nih.gov/pmc/articles/PMC2816958/
https://ncbi.nlm.nih.gov/pubmed/20157612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4110/in.2009.9.6.248