Alum Directly Modulates Murine B Lymphocytes to Produce IgG1 Isotype

Aluminum hydroxide (alum) is the most widely used adjuvant in human vaccines. Nevertheless, it is virtually unknown whether alum acts on B cells. In the present study, we explored the direct effect of alum on Ig expression by murine B cells in vitro. LPS-activated mouse spleen B cells were cultured...

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Autores principales: Jin, Bo-Ra, Kim, Sun-Jin, Lee, Jeong-Min, Kang, Seong-Ho, Han, Hye-Ju, Jang, Young-Saeng, Seo, Goo-young, Kim, Pyeung-Hyeun
Formato: Artigo
Lenguaje:Inglês
Publicado: The Korean Association of Immunologists 2013
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607705/
https://ncbi.nlm.nih.gov/pubmed/23559895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4110/in.2013.13.1.10
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