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Novel Mode of Antagonist Binding in NMDA Receptors Revealed by the Crystal Structure of the GluN1-GluN2A Ligand-Binding Domain Complexed to NVP-AAM077
Competitive antagonists against N-methyl-D-aspartate (NMDA) receptors have played critical roles throughout the history of neuropharmacology and basic neuroscience. There are currently numerous NMDA receptor antagonists containing a variety of chemical groups. Among those compounds, a GluN2-specific...
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| Published in: | Mol Pharmacol |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
The American Society for Pharmacology and Experimental Therapeutics
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5452055/ https://ncbi.nlm.nih.gov/pubmed/28468946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.116.107912 |
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