The chromatin remodelling factor ATRX suppresses R‐loops in transcribed telomeric repeats

ATRX is a chromatin remodelling factor found at a wide range of tandemly repeated sequences including telomeres (TTAGGG)(n). ATRX mutations are found in nearly all tumours that maintain their telomeres via the alternative lengthening of telomere (ALT) pathway, and ATRX is known to suppress this path...

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Bibliografiset tiedot
Julkaisussa:EMBO Rep
Päätekijät: Nguyen, Diu TT, Voon, Hsiao Phin J, Xella, Barbara, Scott, Caroline, Clynes, David, Babbs, Christian, Ayyub, Helena, Kerry, Jon, Sharpe, Jacqueline A, Sloane‐Stanley, Jackie A, Butler, Sue, Fisher, Chris A, Gray, Nicki E, Jenuwein, Thomas, Higgs, Douglas R, Gibbons, Richard J
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2017
Aiheet:
Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5452009/
https://ncbi.nlm.nih.gov/pubmed/28487353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201643078
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