Loss of Atrx Affects Trophoblast Development and the Pattern of X-Inactivation in Extraembryonic Tissues

ATRX is an X-encoded member of the SNF2 family of ATPase/helicase proteins thought to regulate gene expression by modifying chromatin at target loci. Mutations in ATRX provided the first example of a human genetic disease associated with defects in such proteins. To better understand the role of ATR...

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Detalhes bibliográficos
Main Authors: Garrick, David, Sharpe, Jackie A, Arkell, Ruth, Dobbie, Lorraine, Smith, Andrew J. H, Wood, William G, Higgs, Douglas R, Gibbons, Richard J
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440874/
https://ncbi.nlm.nih.gov/pubmed/16628246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0020058
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