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Defining the Cause of Skewed X-Chromosome Inactivation in X-Linked Mental Retardation by Use of a Mouse Model

Extreme skewing of X-chromosome inactivation (XCI) is rare in the normal female population but is observed frequently in carriers of some X-linked mutations. Recently, it has been shown that various forms of X-linked mental retardation (XLMR) have a strong association with skewed XCI in female carri...

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Detalhes bibliográficos
Main Authors: Muers, Mary R. , Sharpe, Jacqueline A. , Garrick, David , Sloane-Stanley, Jacqueline , Nolan, Patrick M. , Hacker, Terry , Wood, William G. , Higgs, Douglas R. , Gibbons, Richard J. 
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Human Genetics 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867101/
https://ncbi.nlm.nih.gov/pubmed/17503331
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