Skewed X-chromosome Inactivation in Scleroderma

Scleroderma is a female-prevalent autoimmune disease of unclear etiology. Two fundamental gender differences, skewed X-chromosome inactivation (XCI) and pregnancy-related microchimerism have been implicated in scleroderma. We investigated the XCI patterns of female scleroderma patients and the paren...

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Main Authors: Uz, Elif, Loubiere, Laurence S, Gadi, Vijayakrishna K., Ozbalkan, Zeynep, Stewart, Jeffrey, Nelson, J. Lee, Ozcelik, Tayfun
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716291/
https://ncbi.nlm.nih.gov/pubmed/18157513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12016-007-8044-z
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