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Analysis of skewed X-chromosome inactivation in females with rheumatoid arthritis and autoimmune thyroid diseases

INTRODUCTION: The majority of autoimmune diseases such as rheumatoid arthritis (RA) and autoimmune thyroid diseases (AITDs) are characterized by a striking female predominance superimposed on a predisposing genetic background. The role of extremely skewed X-chromosome inactivation (XCI) has been que...

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Detalhes bibliográficos
Main Authors: Chabchoub, Ghazi, Uz, Elif, Maalej, Abdellatif, Mustafa, Chigdem A, Rebai, Ahmed, Mnif, Mouna, Bahloul, Zouheir, Farid, Nadir R, Ozcelik, Tayfun, Ayadi, Hammadi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745787/
https://ncbi.nlm.nih.gov/pubmed/19589151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2759
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