The chromatin-remodeling protein ATRX is critical for neuronal survival during corticogenesis

Mutations in genes encoding chromatin-remodeling proteins, such as the ATRX gene, underlie a number of genetic disorders including several X-linked mental retardation syndromes; however, the role of these proteins in normal CNS development is unknown. Here, we used a conditional gene-targeting appro...

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Detalhes bibliográficos
Main Authors: Bérubé, Nathalie G., Mangelsdorf, Marie, Jagla, Magdalena, Vanderluit, Jackie, Garrick, David, Gibbons, Richard J., Higgs, Douglas R., Slack, Ruth S., Picketts, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2005
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC544602/
https://ncbi.nlm.nih.gov/pubmed/15668733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200522329
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