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ATRX Dysfunction Induces Replication Defects in Primary Mouse Cells

The chromatin remodeling protein ATRX, which targets tandem repetitive DNA, has been shown to be required for expression of the alpha globin genes, for proliferation of a variety of cellular progenitors, for chromosome congression and for the maintenance of telomeres. Mutations in ATRX have recently...

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Bibliografische gegevens
Hoofdauteurs: Clynes, David, Jelinska, Clare, Xella, Barbara, Ayyub, Helena, Taylor, Stephen, Mitson, Matthew, Bachrati, Csanád Z., Higgs, Douglas R., Gibbons, Richard J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961441/
https://ncbi.nlm.nih.gov/pubmed/24651726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092915
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