ATRX Dysfunction Induces Replication Defects in Primary Mouse Cells

The chromatin remodeling protein ATRX, which targets tandem repetitive DNA, has been shown to be required for expression of the alpha globin genes, for proliferation of a variety of cellular progenitors, for chromosome congression and for the maintenance of telomeres. Mutations in ATRX have recently...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Clynes, David, Jelinska, Clare, Xella, Barbara, Ayyub, Helena, Taylor, Stephen, Mitson, Matthew, Bachrati, Csanád Z., Higgs, Douglas R., Gibbons, Richard J.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961441/
https://ncbi.nlm.nih.gov/pubmed/24651726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092915
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