Smooth muscle cell-specific deletion of Col15a1 unexpectedly leads to impaired development of advanced atherosclerotic lesions

Atherosclerotic plaque rupture with subsequent embolic events is a major cause of sudden death from myocardial infarction or stroke. Although smooth muscle cells (SMCs) produce and respond to collagens in vitro, there is no direct evidence in vivo that SMCs are a crucial source of collagens and that...

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Gepubliceerd in:Am J Physiol Heart Circ Physiol
Hoofdauteurs: Durgin, Brittany G., Cherepanova, Olga A., Gomez, Delphine, Karaoli, Themistoclis, Alencar, Gabriel F., Butcher, Joshua T., Zhou, Yu-Qing, Bendeck, Michelle P., Isakson, Brant E., Owens, Gary K., Connelly, Jessica J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2017
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451587/
https://ncbi.nlm.nih.gov/pubmed/28283548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00029.2017
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