Smooth muscle cell-specific deletion of Col15a1 unexpectedly leads to impaired development of advanced atherosclerotic lesions

Atherosclerotic plaque rupture with subsequent embolic events is a major cause of sudden death from myocardial infarction or stroke. Although smooth muscle cells (SMCs) produce and respond to collagens in vitro, there is no direct evidence in vivo that SMCs are a crucial source of collagens and that...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Durgin, Brittany G., Cherepanova, Olga A., Gomez, Delphine, Karaoli, Themistoclis, Alencar, Gabriel F., Butcher, Joshua T., Zhou, Yu-Qing, Bendeck, Michelle P., Isakson, Brant E., Owens, Gary K., Connelly, Jessica J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451587/
https://ncbi.nlm.nih.gov/pubmed/28283548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00029.2017
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