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A novel ALS-associated variant in UBQLN4 regulates motor axon morphogenesis

The etiological underpinnings of amyotrophic lateral sclerosis (ALS) are complex and incompletely understood, although contributions to pathogenesis by regulators of proteolytic pathways have become increasingly apparent. Here, we present a novel variant in UBQLN4 that is associated with ALS and sho...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:eLife
Prif Awduron: Edens, Brittany M, Yan, Jianhua, Miller, Nimrod, Deng, Han-Xiang, Siddique, Teepu, Ma, Yongchao C
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: eLife Sciences Publications, Ltd 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451210/
https://ncbi.nlm.nih.gov/pubmed/28463112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.25453
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