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Early Impairment of Synaptic and Intrinsic Excitability in Mice Expressing ALS/Dementia-Linked Mutant UBQLN2

Frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) are believed to represent the different outcomes of a common pathogenic mechanism. However, while researchers have intensely studied the involvement of motor neurons in the ALS/FTD syndrome, very little is known about the function...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Radzicki, Daniel, Liu, Erdong, Deng, Han-Xiang, Siddique, Teepu, Martina, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5028382/
https://ncbi.nlm.nih.gov/pubmed/27703430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2016.00216
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