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A novel ALS-associated variant in UBQLN4 regulates motor axon morphogenesis

The etiological underpinnings of amyotrophic lateral sclerosis (ALS) are complex and incompletely understood, although contributions to pathogenesis by regulators of proteolytic pathways have become increasingly apparent. Here, we present a novel variant in UBQLN4 that is associated with ALS and sho...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Edens, Brittany M, Yan, Jianhua, Miller, Nimrod, Deng, Han-Xiang, Siddique, Teepu, Ma, Yongchao C
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451210/
https://ncbi.nlm.nih.gov/pubmed/28463112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.25453
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