Potent and selective inhibition of pathogenic viruses by engineered ubiquitin variants

The recent Middle East respiratory syndrome coronavirus (MERS-CoV), Ebola and Zika virus outbreaks exemplify the continued threat of (re-)emerging viruses to human health, and our inability to rapidly develop effective therapeutic countermeasures. Many viruses, including MERS-CoV and the Crimean-Con...

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Foilsithe in:PLoS Pathog
Main Authors: Zhang, Wei, Bailey-Elkin, Ben A., Knaap, Robert C. M., Khare, Baldeep, Dalebout, Tim J., Johnson, Garrett G., van Kasteren, Puck B., McLeish, Nigel J., Gu, Jun, He, Wenguang, Kikkert, Marjolein, Mark, Brian L., Sidhu, Sachdev S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2017
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451084/
https://ncbi.nlm.nih.gov/pubmed/28542609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006372
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